Op deze pagina vind je de abstracts van en links naar verschillende nuttige wetenschappelijke artikelen over Tourette.

Tourette syndrome research highlights from 2022

Hartmann A, Andrén P, Atkinson-Clément C et al. Tourette syndrome research highlights from 2022 [version 2; peer review: 3 approved]. F1000Research 2023, 12:826

Abstract

This is the ninth yearly article in the Tourette Syndrome Research Highlights series, summarizing selected research reports from 2022 relevant to Tourette syndrome. The authors briefly summarize reports they consider most important or interesting.

Link naar het artikel: https://f1000research.com/articles/12-826

European clinical guidelines for Tourette Syndrome and other tic disorders. Part I: assessment

Danielle C. CathTammy HedderlyAndrea G. LudolphJeremy S. Stern, Tara MurphyAndreas HartmannVirginie CzerneckiMary May RobertsonDavide MartinoA. MunchauR. Rizzo, and the ESSTS Guidelines Group


Abstract

A working group of the European Society for the Study of Tourette Syndrome (ESSTS) has developed the first European assessment guidelines of Tourette Syndrome (TS). The available literature including national guidelines was thoroughly screened and extensively discussed in the expert group of ESSTS members. Detailed clinical assessment guidelines of tic disorders and their comorbidities in both children and adults are presented. Screening methods that might be helpful and necessary for specialists’ differential diagnosis process are suggested in order to further analyse cognitive abilities, emotional functions and motor skills. Besides clinical interviews and physical examination, additional specific tools (questionnaires, checklists and neuropsychological tests) are recommended.

Keywords: Tics, Tourette, Assessment, Guidelines
 

European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment

Veit RoessnerKerstin J. Plessen, Aribert RothenbergerAndrea G. Ludolph, Renata Rizzo, Liselotte Skov, Gerd Strand, Jeremy S. SternCristiano TerminePieter J. Hoekstra, and the ESSTS Guidelines Group

Abstract
To develop a European guideline on pharmacologic treatment of Tourette syndrome (TS) the available literature was thoroughly screened and extensively discussed by a working group of the European Society for the Study of Tourette syndrome (ESSTS). Although there are many more studies on pharmacotherapy of TS than on behavioral treatment options, only a limited number of studies meets rigorous quality criteria. Therefore, we have devised a two-stage approach. First, we present the highest level of evidence by reporting the findings of existing Cochrane reviews in this field. Subsequently, we provide the first comprehensive overview of all reports on pharmacological treatment options for TS through a MEDLINE, PubMed, and EMBASE search for all studies that document the effect of pharmacological treatment of TS and other tic disorders between 1970 and November 2010. We present a summary of the current consensus on pharmacological treatment options for TS in Europe to guide the clinician in daily practice. This summary is, however, rather a status quo of a clinically helpful but merely low evidence guideline, mainly driven by expert experience and opinion, since rigorous experimental studies are scarce.

Keywords: Tics, Tourette, Pharmacologic, Treatment, Guidelines

European clinical guidelines for Tourette syndrome and other tic disorders. Part III: behavioural and psychosocial interventions

Verdellen C, van de Griendt J, Hartmann A, Murphy T, and the ESSTS Guidelines Group

Abstract
This clinical guideline provides recommendations for the behavioural and psychosocial interventions (BPI) of children and adolescents with tic disorders prepared by a working group of the European Society for the Study of Tourette Syndrome (ESSTS). A systematic literature search was conducted to obtain an update on the efficacy of BPI for tics. Relevant studies were identified using computerised searches of the Medline and PsycINFO databases and the Cochrane Library for the years 1950-2010. The search identified no meta-analyses, yet twelve (systematic) reviews and eight randomised controlled trials provided evidence for the current review. Most evidence was found for habit reversal training (HRT) and the available but smaller evidence also supports the efficacy of exposure with response prevention (ERP). Both interventions are considered first line behavioural treatments for tics for both children and adults and should be offered to a patient, taking into account his preference. Treatments that are considered second line or add-on behavioural treatments are contingency management, function based interventions and relaxation training. Neurofeedback is still experimental. Almost no research was identified that examined the efficacy of psychosocial interventions, e.g., psychoeducation and group work. Based on clinical practice, this guideline recommends behavioural treatment as first line offer to patients in most cases. It should be embedded within a psychoeducational and supportive context and can be combined with drug treatment.